TYRO3

Across TCGA patient cohorts, TYRO3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,689 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TYRO3-associated proteins across cancer lineages are HLA-F, ZZEF1, and TTLL12. Each is linked with TYRO3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TYRO3-to-partner and partner-to-TYRO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYRO3 versus HLA-F in CCRCC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYRO3→partner) and Y-score (partner→TYRO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HLA-F →	-0.564	-0.438	<.001	<.001	3	5
BRCA	ZZEF1 →	-0.204	-0.583	.005	.001	3	4
HNSC	TTLL12 →	+0.388	+0.574	<.001	<.001	3	4
BRCA	UFD1_S247 →	+0.680	+0.557	<.001	.001	3	4
LSCC	UTP4 →	+0.362	+0.629	<.001	<.001	3	4
LSCC	VGLL4_S58 →	+0.839	+0.708	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,689 associations by consensus.

TYRO3 vs HLA-F — CCRCC

Explore this scatter interactively →