TYRO3

Across TCGA patient cohorts, TYRO3 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TYRO3-associated proteins across cancer lineages are DAB2_S723, HSPB8, and LYSMD2. Each is linked with TYRO3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TYRO3-to-partner and partner-to-TYRO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYRO3 versus DAB2_S723 in HNSC, with a Pearson correlation of 0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYRO3→partner) and Y-score (partner→TYRO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DAB2_S723 →	+1.031	+0.697	<.001	<.001	3	4
OV	HSPB8 →	+0.604	+0.583	<.001	<.001	3	3
HNSC	LYSMD2 →	+0.538	+0.439	<.001	<.001	3	3
OV	MARCKS_S101 →	+0.614	+0.418	.001	.005	3	3
OV	MPP1 →	+0.609	+0.731	<.001	<.001	3	3
HNSC	DAB2 →	+0.581	+0.585	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,794 associations by consensus.

TYRO3 vs DAB2_S723 — HNSC

Explore this scatter interactively →