TYRO3

Across TCGA cell cohorts, TYRO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,958 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TYRO3-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Negative regulation of toll-like receptor signaling pathway, and DNA replication initiation. Each is linked with TYRO3 in more than 11 cancer types. Because this analysis shows association rather than direction, both TYRO3-to-partner and partner-to-TYRO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by TYRO3-low versus TYRO3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYRO3→partner) and Y-score (partner→TYRO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.094	+0.595	.003	.004	3	12
OESOPHAGUS	Negative regulation of toll-like receptor signaling pathway →	+0.096	+1.087	.002	.001	3	11
PANCREAS	DNA replication initiation →	+0.131	+0.856	.003	.001	3	10
OESOPHAGUS	Mitotic sister chromatid segregation →	+0.107	+0.871	.003	.002	3	10
KIDNEY	Cellular response to cisplatin →	+0.153	+1.285	<.001	<.001	3	10
OESOPHAGUS	Sister chromatid segregation →	+0.088	+0.892	.004	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,958 associations by consensus.

DNA replication-dependent chromatin assembly by TYRO3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →