TYMS

Across TCGA cell cohorts, TYMS RNA expression is significantly associated with the go_rna of many other GO terms, with 5,001 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TYMS-associated GO terms across cancer lineages are Regulation of mitotic nuclear division, Immunoglobulin heavy chain V-D-J recombination, and Double-strand break repair via break-induced replication. Each is linked with TYMS in more than 18 cancer types. Because this analysis shows association rather than direction, both TYMS-to-partner and partner-to-TYMS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic nuclear division grouped by TYMS-low versus TYMS-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYMS→partner) and Y-score (partner→TYMS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mitotic nuclear division →	+0.123	+1.076	<.001	<.001	3	19
SOFT_TISSUE	Immunoglobulin heavy chain V-D-J recombination →	+0.173	+1.269	<.001	<.001	3	19
BONE	Double-strand break repair via break-induced replication →	+0.287	+1.469	<.001	.003	3	19
BONE	Sister chromatid segregation →	+0.148	+1.450	.003	.003	3	19
BONE	Nuclear chromosome segregation →	+0.133	+1.342	.009	.007	3	19
LUNG_NSCLC_LUSC	Nuclear division →	+0.078	+1.770	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,001 associations by consensus.

Regulation of mitotic nuclear division by TYMS expression — SOFT_TISSUE

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