TXNIP

Across TCGA patient cohorts, TXNIP RNA expression is significantly associated with the protein abundance of many other proteins, with 18,914 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNIP-associated proteins across cancer lineages are CLPX, CSE1L, and CEBPZ. Each is linked with TXNIP in more than 8 cancer types. Because this analysis shows association rather than direction, both TXNIP-to-partner and partner-to-TXNIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNIP versus CLPX in LUAD, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNIP→partner) and Y-score (partner→TXNIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CLPX →	-0.344	-0.800	<.001	<.001	3	9
UCEC	CSE1L →	-0.373	-0.987	<.001	<.001	3	8
BRCA	CEBPZ →	-0.375	-0.843	<.001	<.001	3	7
LUAD	DYNC1LI2_S194 →	-0.494	-0.698	<.001	<.001	3	7
BRCA	KPNA2 →	-0.669	-0.925	<.001	<.001	3	7
LUAD	TOP2A_S1247 →	-0.916	-0.737	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,914 associations by consensus.

TXNIP vs CLPX — LUAD

Explore this scatter interactively →