TXNDC12

Across TCGA patient cohorts, TXNDC12 mutation is significantly associated with the RNA expression of many other genes, with 352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXNDC12-associated genes across cancer lineages are RNA5SP407, MIR6803, and MIR6775. Each is linked with TXNDC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TXNDC12-to-partner and partner-to-TXNDC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP407 grouped by TXNDC12-low versus TXNDC12-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC12→partner) and Y-score (partner→TXNDC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP407 →	+0.397	+7.640	<.001	.009	3	2
UCEC	MIR6803 →	+0.300	+5.741	<.001	<.001	3	1
UCEC	MIR6775 →	+0.629	+3.112	<.001	<.001	3	1
UCEC	PRAMEF13 →	+0.032	+3.716	<.001	.002	3	1
UCEC	CWC25 →	+0.475	+3.337	.006	.005	3	1
UCEC	MIR6870 →	+0.459	+2.589	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 352 associations by consensus.

RNA5SP407 by TXNDC12 expression — BLCA

Explore this box plot interactively →