TXN

Across TCGA cell cohorts, TXN protein abundance is significantly associated with the RNA expression of many other genes, with 4,146 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TXN-associated genes across cancer lineages are AKR1C1, ISCA1, and TXNRD1. Each is linked with TXN in more than 6 cancer types. Because this analysis shows association rather than direction, both TXN-to-partner and partner-to-TXN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXN versus AKR1C1 in LUNG_NSCLC_LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXN→partner) and Y-score (partner→TXN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	AKR1C1 →	+3.731	+1.351	.004	.003	3	7
PANCREAS	ISCA1 →	+0.894	+1.742	.005	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	TXNRD1 →	+2.126	+2.083	.003	.001	3	6
PANCREAS	MRRF →	+0.628	+1.400	.004	<.001	3	6
KIDNEY	UGDH →	+1.992	+1.088	.001	.003	3	6
UPPER_AERODIGESTIVE_TRACT	EIF3E →	+0.859	+1.589	.008	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,146 associations by consensus.

TXN vs AKR1C1 — LUNG_NSCLC_LUAD

Explore this scatter interactively →