TXK

Across TCGA cell cohorts, TXK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,419 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TXK-associated GO terms across cancer lineages are Rho protein signal transduction, Viral process, and Small GTPase-mediated signal transduction. Each is linked with TXK in more than 10 cancer types. Because this analysis shows association rather than direction, both TXK-to-partner and partner-to-TXK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rho protein signal transduction grouped by TXK-low versus TXK-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXK→partner) and Y-score (partner→TXK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Rho protein signal transduction →	+0.131	+1.063	.008	.001	2	11
SOFT_TISSUE	Viral process →	+0.066	+0.544	<.001	.001	3	10
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.065	+1.060	.007	.004	3	9
PANCREAS	Viral budding →	+0.102	+0.910	.001	.009	3	9
OESOPHAGUS	Negative regulation of stress fiber assembly →	+0.182	+0.936	.001	.006	3	9
LARGE_INTESTINE	Cellular response to abiotic stimulus →	+0.026	+0.492	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,419 associations by consensus.

Rho protein signal transduction by TXK expression — OESOPHAGUS

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