TXK

Across TCGA pan-cancer cohorts, TXK RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TXK’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TXK RNA is repressed in tumor relative to normal tissue. In most cancer types TXK is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KIRP are the cancer types where TXK tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TXK RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.691	<.001	8	view →
LUSC	Female	II,III,IV	−1.250	<.001	7	view →
KIRP	All	All	−0.624	<.001	6	view →
BRCA	All	III,IV	−0.353	<.001	6	view →
COAD	All	All	−0.245	.007	4	view →
HNSC	Male	II,III,IV	−0.180	.012	4	view →
KICH	Male	III,IV	−1.242	.047	1	view →
CHOL	All	All	+0.423	.040	1	view →
KIRC	All	III,IV	−0.380	.034	1	view →
STAD	All	All	+0.347	.037	1	view →
THCA	Female	II,III,IV	−0.335	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TXK–LUAD

Open the LUAD breakdown →