TVP23C-CDRT4

Across TCGA patient cohorts, TVP23C-CDRT4 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TVP23C-CDRT4-associated genes across cancer lineages are MAGI2-AS1, MIR6128, and KRTAP15-1. Each is linked with TVP23C-CDRT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TVP23C-CDRT4-to-partner and partner-to-TVP23C-CDRT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGI2-AS1 grouped by TVP23C-CDRT4-low versus TVP23C-CDRT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TVP23C-CDRT4→partner) and Y-score (partner→TVP23C-CDRT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAGI2-AS1 →	+0.244	+5.453	.003	.002	3	2
BRCA	MIR6128 →	+0.743	+8.471	<.001	.005	3	1
UCEC	KRTAP15-1 →	+0.123	+4.621	<.001	.008	3	1
UCEC	RNA5SP516 →	+0.508	+4.937	<.001	.005	3	1
UCEC	RNU6-742P →	+0.698	+5.262	<.001	.001	3	1
UCEC	RNU6-517P →	+0.692	+4.694	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

MAGI2-AS1 by TVP23C-CDRT4 expression — UCEC

Explore this box plot interactively →