TVP23C-CDRT4

Across TCGA pan-cancer cohorts, TVP23C-CDRT4 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated TVP23C-CDRT4 data layer compared with 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher TVP23C-CDRT4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TVP23C-CDRT4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

LUSC, SKCM, and UCS are the cancer types where TVP23C-CDRT4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.311	0.482	<.001	106	view →
SKCM	OS	Median	III,IV	0.500	0.258	.002	38	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
LIHC	OS	Tertile	II,III,IV	0.311	0.737	<.001	35	view →
HNSC	OS	Quartile	III,IV	0.382	0.736	<.001	34	view →
LGG	OS	Median	All	0.742	0.872	<.001	30	view →
UVM	OS	Median	II,III,IV	0.795	0.409	.006	25	view →
STAD	OS	Tertile	III,IV	0.746	0.493	.008	25	view →
BRCA	DFS	Quartile	III,IV	0.947	0.784	.005	19	view →
PRAD	DFS	Median	All	0.890	0.672	<.001	18	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.213	.004	17	view →
KIRC	DFS	Median	All	0.858	0.737	.005	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

TVP23C-CDRT4–LUSC (OS)

Open the LUSC breakdown →