TVP23C-CDRT4

Across TCGA pan-cancer cohorts, TVP23C-CDRT4 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of TVP23C-CDRT4’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TVP23C-CDRT4 RNA is repressed in tumor relative to normal tissue. In most cancer types TVP23C-CDRT4 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and HNSC are the cancer types where TVP23C-CDRT4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TVP23C-CDRT4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.418	<.001	9	view →
KICH	Female	All	−0.220	<.001	6	view →
HNSC	Male	All	+0.153	<.001	6	view →
KIRP	All	II,III,IV	+0.283	.010	5	view →
CHOL	All	All	+0.127	.012	4	view →
LUAD	All	All	+0.083	.001	4	view →
LUSC	All	All	+0.113	.008	3	view →
BLCA	All	III,IV	+0.134	.023	1	view →
ESCA	Female	All	+0.106	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

TVP23C-CDRT4–THCA

Open the THCA breakdown →