TVP23A

Across TCGA cell cohorts, TVP23A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TVP23A-associated genes across cancer lineages are WFDC6, GYPA, and CFHR2. Each is linked with TVP23A in more than 1 cancer types. Because this analysis shows association rather than direction, both TVP23A-to-partner and partner-to-TVP23A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC6 grouped by TVP23A-low versus TVP23A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TVP23A→partner) and Y-score (partner→TVP23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1
LARGE_INTESTINE	GYPA →	+0.121	+3.793	<.001	.007	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

WFDC6 by TVP23A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →