TUSC8

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TUSC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,351 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TUSC8-associated proteins across cancer lineages are DDAH1, SMAP1, and UPP1. Each is linked with TUSC8 in more than 3 cancer types. Because this analysis shows association rather than direction, both TUSC8-to-partner and partner-to-TUSC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUSC8 versus DDAH1 in HNSC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TUSC8→partner) and Y-score (partner→TUSC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCDDAH1 →+0.554+0.728<.001<.00134
GBMSMAP1 →+0.279+0.130<.001<.00134
HNSCUPP1 →-0.768-0.551.001.00234
PDACNDRG2 →+0.376+0.271<.001.00134
COADSUCLA2 →+0.435+1.842<.001<.00134
PDACWDR13 →+0.167+0.372<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,351 associations by consensus.

TUSC8 vs DDAH1 — HNSC

Per-sample scatter of TUSC8 vs DDAH1 in HNSC (Pearson r = 0.49).

Explore this scatter interactively →

Exploration