TULP1

Across TCGA pan-cancer cohorts, TULP1 Mutation is linked to patient survival in 9 of 34 cancer types, making it a survival-associated TULP1 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TULP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TULP1 expression acts as an unfavorable survival marker.

LUAD, ESCA, and CHOL are the cancer types where TULP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.246	0.792	<.001	27	view →
ESCA	DFS	Median	All	0.147	0.535	.010	18	view →
CHOL	OS	Median	All	0.154	0.793	.004	9	view →
MESO	DFS	Median	All	0.099	0.392	.030	9	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
PRAD	DFS	Median	All	0.085	0.774	.001	6	view →
STAD	OS	Median	III,IV	0.003	0.630	<.001	6	view →
UCEC	OS	Median	IV	0.346	0.764	<.001	6	view →
SKCM	OS	Median	IV	0.415	0.861	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

TULP1–LUAD (DFS)

Open the LUAD breakdown →