TUBB8

Across TCGA patient cohorts, TUBB8 protein abundance is significantly associated with the RNA expression of many other genes, with 3,096 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TUBB8-associated genes across cancer lineages are CHST14, CFL1P4, and RN7SL477P. Each is linked with TUBB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBB8-to-partner and partner-to-TUBB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBB8 versus CHST14 in COAD, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB8→partner) and Y-score (partner→TUBB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CHST14 →	+0.636	+0.966	.008	.002	3	2
OV	CFL1P4 →	+0.691	+0.976	.008	<.001	3	2
GBM	RN7SL477P →	+0.415	+0.335	.002	.008	3	2
OV	LDHA →	+0.695	+0.940	.002	.004	3	2
OV	RPSAP19 →	+1.306	+0.940	.006	.001	3	2
OV	PRDM11 →	-0.672	-0.776	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,096 associations by consensus.

TUBB8 vs CHST14 — COAD

Explore this scatter interactively →