TUBB8

Across TCGA cell cohorts, TUBB8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,912 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TUBB8-associated GO terms across cancer lineages are Regulation of body fluid levels, Negative regulation of gene expression, epigenetic, and Renal system process. Each is linked with TUBB8 in more than 9 cancer types. Because this analysis shows association rather than direction, both TUBB8-to-partner and partner-to-TUBB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of body fluid levels grouped by TUBB8-low versus TUBB8-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB8→partner) and Y-score (partner→TUBB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of body fluid levels →	-0.101	-0.739	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.055	+0.304	<.001	.002	3	9
SOFT_TISSUE	Renal system process →	-0.081	-0.508	<.001	.002	3	8
BREAST	Regulation of monoatomic ion transmembrane transport →	-0.052	-0.754	.008	.007	3	8
OVARY	Positive regulation of double-strand break repair →	+0.056	+0.381	.006	.001	2	9
BREAST	Regulation of monoatomic cation transmembrane transport →	-0.047	-0.451	<.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,912 associations by consensus.

Regulation of body fluid levels by TUBB8 expression — BREAST

Explore this box plot interactively →