TUBB4A

Across TCGA cell cohorts, TUBB4A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,717 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TUBB4A-associated GO terms across cancer lineages are Positive regulation of sodium ion transmembrane transport, Locomotory exploration behavior, and Positive regulation of monoatomic ion transport. Each is linked with TUBB4A in more than 15 cancer types. Because this analysis shows association rather than direction, both TUBB4A-to-partner and partner-to-TUBB4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of sodium ion transmembrane transport grouped by TUBB4A-low versus TUBB4A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB4A→partner) and Y-score (partner→TUBB4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of sodium ion transmembrane transport →	-0.273	-3.992	<.001	<.001	3	16
OESOPHAGUS	Locomotory exploration behavior →	+0.248	+2.065	.001	<.001	3	14
BONE	Positive regulation of monoatomic ion transport →	-0.120	-2.907	<.001	<.001	3	14
OESOPHAGUS	Potassium ion import across plasma membrane →	-0.266	-2.383	<.001	.002	3	14
BREAST	Cytoplasmic translation →	+0.083	+0.960	<.001	.004	3	14
STOMACH	Tetrapyrrole biosynthetic process →	+0.103	+2.470	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,717 associations by consensus.

Positive regulation of sodium ion transmembrane transport by TUBB4A expression — BONE

Explore this box plot interactively →