TUBA3E

Across TCGA patient cohorts, TUBA3E mutation is significantly associated with the RNA expression of many other genes, with 2,196 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBA3E-associated genes across cancer lineages are RNU6-162P, RNU1-17P, and LINC01072. Each is linked with TUBA3E in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA3E-to-partner and partner-to-TUBA3E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-162P grouped by TUBA3E-low versus TUBA3E-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA3E→partner) and Y-score (partner→TUBA3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU6-162P →	+0.487	+4.274	<.001	.001	3	2
UCEC	RNU1-17P →	+0.214	+2.283	<.001	.001	3	2
UCEC	LINC01072 →	+0.118	+2.096	<.001	.001	3	2
UCEC	RN7SL392P →	+0.122	+2.044	.001	.004	3	2
LUAD	RNU6ATAC33P →	+0.218	+5.912	<.001	.001	3	2
LUAD	VTRNA2-2P →	+0.291	+4.554	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,196 associations by consensus.

RNU6-162P by TUBA3E expression — STAD

Explore this box plot interactively →