TUBA3E

Across TCGA pan-cancer cohorts, TUBA3E RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated TUBA3E data layer compared with 5 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TUBA3E RNA is associated with better overall survival. In most high-consensus cancer types, elevated TUBA3E expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCEC show a favorable association.

BRCA, UCEC, and THCA are the cancer types where TUBA3E RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.948	0.898	<.001	115	view →
UCEC	DFS	Median	IV	0.868	0.497	.003	82	view →
THCA	OS	Tertile	All	0.943	0.995	.002	43	view →
LIHC	OS	Tertile	III,IV	0.383	0.725	.002	37	view →
LGG	OS	Median	All	0.756	0.854	.001	28	view →
BLCA	DFS	Median	II,III,IV	0.451	0.553	.008	27	view →
KICH	OS	Quartile	II,III,IV	0.637	0.931	<.001	27	view →
COAD	OS	Median	II,III,IV	0.778	0.900	.005	26	view →
LUAD	DFS	Median	IV	0.527	0.846	.007	20	view →
THYM	DFS	Median	III,IV	1.000	0.402	.004	18	view →
READ	DFS	Tertile	II,III,IV	0.665	0.950	.020	18	view →
PAAD	DFS	Quartile	II,III,IV	0.450	0.278	.013	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

TUBA3E–BRCA (OS)

Open the BRCA breakdown →