TUBA3E

Across TCGA pan-cancer cohorts, TUBA3E RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TUBA3E’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TUBA3E RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBA3E is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

BRCA, UCEC, and KIRC are the cancer types where TUBA3E tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUBA3E RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.830	<.001	8	view →
UCEC	All	II,III,IV	−1.421	.002	6	view →
KIRC	All	All	+0.714	<.001	6	view →
THCA	All	II,III,IV	−0.066	.011	4	view →
COAD	Female	II,III,IV	+0.101	.008	3	view →
LUSC	All	All	+0.323	.037	2	view →
LIHC	Female	All	+0.269	.018	2	view →
BLCA	Male	All	+0.053	.043	2	view →
READ	All	II,III,IV	+0.114	.033	1	view →
KICH	Female	All	−0.042	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TUBA3E–BRCA

Open the BRCA breakdown →