TUBA1C

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TUBA1C protein abundance is significantly associated with the RNA expression of many other genes, with 18,530 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TUBA1C-associated genes across cancer lineages are CENPA, UBE2C, and FAM136A. Each is linked with TUBA1C in more than 5 cancer types. Because this analysis shows association rather than direction, both TUBA1C-to-partner and partner-to-TUBA1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBA1C versus CENPA in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1C→partner) and Y-score (partner→TUBA1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCENPA →+0.949+0.213<.001.00536
LUADUBE2C →+1.292+0.189.003.00136
LSCCFAM136A →+0.570+0.312<.001<.00136
OVTPX2 →+1.381+0.342<.001<.00136
OVANLN →+1.279+0.336<.001<.00135
LSCCMPHOSPH10 →+0.580+0.268<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,530 associations by consensus.

TUBA1C vs CENPA — OV

Per-sample scatter of TUBA1C vs CENPA in OV (Pearson r = 0.38).

Explore this scatter interactively →

Exploration