TUBA1C

Across TCGA patient cohorts, TUBA1C mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBA1C-associated genes across cancer lineages are CD4+ naive T-cells, naive B-cells, and aDC. Each is linked with TUBA1C in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA1C-to-partner and partner-to-TUBA1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ naive T-cells grouped by TUBA1C-low versus TUBA1C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1C→partner) and Y-score (partner→TUBA1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD4+ naive T-cells →	+0.032	+6.142	<.001	.027	3	1
READ	naive B-cells →	+0.019	+4.039	<.001	.016	3	1
UCEC	aDC →	+0.089	+2.180	.020	.036	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ naive T-cells by TUBA1C expression — COAD

Explore this box plot interactively →