TUBA1C

Across TCGA cell cohorts, TUBA1C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,160 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TUBA1C-associated GO terms across cancer lineages are Establishment or maintenance of microtubule cytoskeleton polarity, Positive regulation of mitotic cell cycle phase transition, and Regulation of mitotic spindle checkpoint. Each is linked with TUBA1C in more than 17 cancer types. Because this analysis shows association rather than direction, both TUBA1C-to-partner and partner-to-TUBA1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of microtubule cytoskeleton polarity grouped by TUBA1C-low versus TUBA1C-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1C→partner) and Y-score (partner→TUBA1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment or maintenance of microtubule cytoskeleton polarity →	+0.202	+1.190	<.001	<.001	3	18
BONE	Positive regulation of mitotic cell cycle phase transition →	+0.108	+1.057	.001	<.001	3	16
BREAST	Regulation of mitotic spindle checkpoint →	+0.140	+0.826	<.001	<.001	3	16
BREAST	Regulation of mitotic cell cycle spindle assembly checkpoint →	+0.140	+0.826	<.001	<.001	3	16
URINARY_TRACT	Regulation of spindle checkpoint →	+0.182	+1.637	<.001	<.001	3	16
URINARY_TRACT	Mitotic spindle elongation →	+0.230	+1.158	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,160 associations by consensus.

Establishment or maintenance of microtubule cytoskeleton polarity by TUBA1C expression — URINARY_TRACT

Explore this box plot interactively →