TUB

Across TCGA cell cohorts, TUB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,388 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TUB-associated GO terms across cancer lineages are DNA-templated transcription initiation, Transcription initiation at RNA polymerase II promoter, and Nucleoside triphosphate biosynthetic process. Each is linked with TUB in more than 13 cancer types. Because this analysis shows association rather than direction, both TUB-to-partner and partner-to-TUB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by TUB-low versus TUB-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUB→partner) and Y-score (partner→TUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA-templated transcription initiation →	+0.060	+1.680	<.001	<.001	3	14
URINARY_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.069	+1.807	<.001	<.001	3	14
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.115	+1.528	<.001	<.001	3	14
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.127	+1.528	<.001	<.001	3	14
BONE	Heterochromatin formation →	+0.081	+1.023	<.001	.009	3	13
LUNG_NSCLC_LUSC	tRNA transcription →	+0.125	+1.562	.002	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,388 associations by consensus.

DNA-templated transcription initiation by TUB expression — OESOPHAGUS

Explore this box plot interactively →