TTTY8

Across TCGA patient cohorts, TTTY8 RNA expression is significantly associated with the mutation status of many other genes, with 211 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TTTY8-associated genes across cancer lineages are SUSD4, KRT6A, and UGT1A9. Each is linked with TTTY8 in more than 3 cancer types. Because this analysis shows association rather than direction, both TTTY8-to-partner and partner-to-TTTY8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUSD4 grouped by TTTY8-low versus TTTY8-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY8→partner) and Y-score (partner→TTTY8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SUSD4 →	+7.473	+0.039	.007	<.001	3	4
LUAD	KRT6A →	+4.014	+0.009	.007	<.001	3	2
BRCA	UGT1A9 →	+8.057	+0.053	.005	<.001	3	2
KIRC	ZC3H18 →	+8.025	+0.064	.007	<.001	3	2
KIRC	OTOGL →	+8.025	+0.039	.007	<.001	3	2
SKCM	SUPT6H →	+3.263	+0.009	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 211 associations by consensus.

SUSD4 by TTTY8 expression — BRCA

Explore this box plot interactively →