Q-omics provides the consensus-scored TTTY1 profile across patient tissues and cancer cell-line models. TTTY1 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, TTTY1 protein abundance shows 6,112 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight MESO, and HNSC as cancer lineages where TTTY1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TTTY1 survival associations across molecular data types. TTTY1 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TTTY1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	MESO (36)	view →

This table ranks reproducible TTTY1 RNA expression–survival associations across cancer types. High TTTY1 expression shows unfavorable associations in MESO, STAD, LUAD, SARC and LIHC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for TTTY1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	II,III,IV	0.039	0.407	<.001	36	view →
STAD	OS	Tertile	II,III,IV	0.169	0.710	.001	36	view →
LUAD	OS	Tertile	All	0.241	0.673	.011	36	view →
SARC	OS	Tertile	All	0.029	0.839	<.001	36	view →
LIHC	OS	Tertile	All	0.028	0.775	<.001	36	view →

Pink = unfavorable, green = favorable. all 5 lineages →

TTTY1-MESO (DFS)

Kaplan–Meier survival curve for TTTY1 RNA expression in MESO: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TTTY1 in patient tissues and cancer cell lines. In patient samples, TTTY1 shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼Protein (mass-spec)
Protein (mass-spec)	6,112	HNSC (6112)	view →
RNA	1,560	HNSC (1560)	view →
▼RNA
RNA	204	HNSC (104)	view →
Mutation	138	BRCA (83)	view →