TTTY1

Across TCGA patient cohorts, TTTY1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,560 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TTTY1-associated genes across cancer lineages are SNRPD3, MFNG, and HMGXB4. Each is linked with TTTY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY1-to-partner and partner-to-TTTY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTTY1 versus SNRPD3 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY1→partner) and Y-score (partner→TTTY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNRPD3 →	-0.516	-2.048	.008	<.001	3	1
HNSC	MFNG →	+0.731	+1.348	.001	.001	3	1
HNSC	HMGXB4 →	-0.565	-1.485	.005	.001	3	1
HNSC	GRAP2 →	+0.832	+1.655	.001	.001	3	1
HNSC	PVALB →	+0.487	+2.083	.003	.002	3	1
HNSC	IL2RB →	+0.945	+1.696	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,560 associations by consensus.

TTTY1 vs SNRPD3 — HNSC

Explore this scatter interactively →