TTLL11

Across TCGA patient cohorts, TTLL11 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,888 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTLL11-associated proteins across cancer lineages are PDIA6, PDIA4, and HSP90B1. Each is linked with TTLL11 in more than 5 cancer types. Because this analysis shows association rather than direction, both TTLL11-to-partner and partner-to-TTLL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTLL11 versus PDIA6 in GBM, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL11→partner) and Y-score (partner→TTLL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDIA6 →	-0.411	-0.565	<.001	<.001	3	6
BRCA	PDIA4 →	-0.381	-0.311	<.001	.005	3	6
BRCA	HSP90B1 →	-0.395	-0.370	<.001	.001	3	6
GBM	PDIA3 →	-0.338	-0.587	<.001	<.001	3	5
GBM	ZER1 →	+0.265	+0.392	.003	.005	2	6
BRCA	PTPA →	+0.315	+0.494	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,888 associations by consensus.

TTLL11 vs PDIA6 — GBM

Explore this scatter interactively →