TTI2

Across TCGA patient cohorts, TTI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,860 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTI2-associated proteins across cancer lineages are CCAR2, PBK, and XPO7. Each is linked with TTI2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TTI2-to-partner and partner-to-TTI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTI2 versus CCAR2 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTI2→partner) and Y-score (partner→TTI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCAR2 →	+0.398	+0.493	<.001	<.001	3	6
COAD	PBK →	+0.717	+0.678	<.001	<.001	3	6
OV	XPO7 →	+0.359	+0.527	<.001	<.001	3	5
OV	STRBP →	+0.417	+0.428	.003	.004	3	5
LSCC	MAK16 →	+0.404	+0.453	<.001	<.001	3	5
COAD	ELP3 →	+0.274	+0.537	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,860 associations by consensus.

TTI2 vs CCAR2 — LSCC

Explore this scatter interactively →