TTI1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TTI1 protein abundance is significantly associated with the protein abundance of many other proteins, with 29,572 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTI1-associated proteins across cancer lineages are NAT10, NCL_S67, and TELO2. Each is linked with TTI1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TTI1-to-partner and partner-to-TTI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTI1 versus NAT10 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTI1→partner) and Y-score (partner→TTI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCANAT10 →+0.318+0.199<.001<.00139
LUADNCL_S67 →+0.952+0.223<.001<.00139
BRCATELO2 →+0.348+0.343<.001<.00139
LUADMCM4 →+0.788+0.308<.001<.00139
OVDDX21_S89 →+1.798+0.518<.001<.00139
BRCAHEATR1 →+0.335+0.246<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 29,572 associations by consensus.

TTI1 vs NAT10 — BRCA

Per-sample scatter of TTI1 vs NAT10 in BRCA (Pearson r = 0.41).

Explore this scatter interactively →

Exploration