TTF2

Across TCGA patient cohorts, TTF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,868 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTF2-associated proteins across cancer lineages are SMC2, SMC4, and TRIM33_S862. Each is linked with TTF2 in more than 8 cancer types. Because this analysis shows association rather than direction, both TTF2-to-partner and partner-to-TTF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTF2 versus SMC2 in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTF2→partner) and Y-score (partner→TTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC2 →	+0.746	+0.462	<.001	<.001	3	9
GBM	SMC4 →	+0.699	+0.434	<.001	.001	3	9
LSCC	TRIM33_S862 →	+0.607	+0.721	<.001	<.001	3	9
UCEC	TOP2A →	+1.078	+0.994	<.001	<.001	3	9
UCEC	RRM2_S20 →	+1.472	+0.818	<.001	<.001	3	8
LUAD	RRP36_S73 →	+0.977	+0.532	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,868 associations by consensus.

TTF2 vs SMC2 — GBM

Explore this scatter interactively →