TTC9B

Across TCGA patient cohorts, TTC9B mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TTC9B-associated genes across cancer lineages are MIR520G, CXorf51A, and RN7SL811P. Each is linked with TTC9B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC9B-to-partner and partner-to-TTC9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR520G grouped by TTC9B-low versus TTC9B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC9B→partner) and Y-score (partner→TTC9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR520G →	+0.308	+7.924	.002	.008	3	1
LUSC	CXorf51A →	+0.084	+7.924	<.001	.008	3	1
BLCA	RN7SL811P →	+0.223	+5.177	<.001	.007	3	1
BLCA	FAM106DP →	+0.109	+5.106	<.001	.008	3	1
BLCA	ARF4P3 →	+0.136	+4.973	<.001	.009	3	1
BLCA	MIR875 →	+0.678	+5.685	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

MIR520G by TTC9B expression — LUSC

Explore this box plot interactively →