TTC9B

Across TCGA cell cohorts, TTC9B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,546 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC9B-associated GO terms across cancer lineages are Organic acid transport, Carboxylic acid transport, and Positive regulation of mitochondrial membrane permeability. Each is linked with TTC9B in more than 4 cancer types. Because this analysis shows association rather than direction, both TTC9B-to-partner and partner-to-TTC9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organic acid transport grouped by TTC9B-low versus TTC9B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC9B→partner) and Y-score (partner→TTC9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Organic acid transport →	-0.022	-0.073	<.001	<.001	3	5
BLOOD_Leukemia	Carboxylic acid transport →	-0.022	-0.073	<.001	<.001	3	5
BLOOD_Leukemia	Positive regulation of mitochondrial membrane permeability →	+0.076	+0.066	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Receptor recycling →	+0.073	+0.138	<.001	.001	3	4
BLOOD_Myeloma	Hematopoietic stem cell homeostasis →	+0.077	+0.174	<.001	.006	3	4
SKIN	Regulation of potassium ion export across plasma membrane →	-0.179	-0.280	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,546 associations by consensus.

Organic acid transport by TTC9B expression — BLOOD_Leukemia

Explore this box plot interactively →