TTC7B

Across TCGA cell cohorts, TTC7B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,774 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TTC7B-associated GO terms across cancer lineages are Microtubule polymerization or depolymerization, tRNA transcription, and Protein depolymerization. Each is linked with TTC7B in more than 13 cancer types. Because this analysis shows association rather than direction, both TTC7B-to-partner and partner-to-TTC7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization or depolymerization grouped by TTC7B-low versus TTC7B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC7B→partner) and Y-score (partner→TTC7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Microtubule polymerization or depolymerization →	+0.093	+2.789	.006	<.001	3	13
STOMACH	tRNA transcription →	+0.110	+2.229	.005	.004	2	14
BREAST	Protein depolymerization →	+0.104	+1.116	<.001	.001	3	13
STOMACH	Positive regulation of supramolecular fiber organization →	+0.085	+2.276	<.001	.002	3	12
STOMACH	DNA-templated transcription initiation →	+0.072	+2.729	<.001	<.001	3	12
SKIN	Actin filament depolymerization →	+0.166	+0.828	<.001	.003	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,774 associations by consensus.

Microtubule polymerization or depolymerization by TTC7B expression — STOMACH

Explore this box plot interactively →