Q-omics provides the consensus-scored TTC41P profile across patient tissues and cancer cell-line models. TTC41P expression is associated with patient survival in 27 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, TTC41P is differentially expressed in 11, with the highest sampling consensus in THCA. Additionally, TTC41P RNA expression shows 19,619 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight SKCM, THCA, and UVM as cancer lineages where TTC41P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TTC41P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TTC41P survival associations across molecular data types. TTC41P RNA expression shows survival associations in the most cancer types (27), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TTC41P RNA expression–survival associations across cancer types. High TTC41P expression shows unfavorable associations in KIRC, LGG and ESCA, but favorable associations in SKCM, BRCA and READ. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for TTC41P RNA expression.
This table summarizes TTC41P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for TTC41P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TTC41P shows lower tumor expression in THCA and KICH and higher tumor expression in HNSC, LIHC, BRCA and BLCA. The THCA box plot shows higher TTC41P RNA expression in normal versus tumor tissue (log2 FC = −0.772, t-test p < 0.001).
This table shows molecular features associated with TTC41P in patient tissues and cancer cell lines. In patient samples, TTC41P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
