Across TCGA patient cohorts, TTC41P mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC41P-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and MEK1. Each is linked with TTC41P in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC41P-to-partner and partner-to-TTC41P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC41P→partner) and Y-score (partner→TTC41P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.309	-3.700	.008	.001	3	1
UCEC	A-Raf_pS299 →	-0.120	-3.169	.032	.019	3	1
UCEC	MEK1 →	+0.417	+3.321	.014	.010	3	1
UCEC	mTOR_pS2448 →	-0.179	-2.986	.010	.035	3	1
UCEC	p62 Lck ligand →	+0.403	+3.169	.007	.018	3	1
UCEC	p70-S6K_pT389 →	-0.201	-2.312	.023	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

TTC41P survival (RNA) · tumor vs normal (RNA) · all TTC41P data types