TTC39C

Across TCGA patient cohorts, TTC39C mutation is significantly associated with the RNA expression of many other genes, with 3,215 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC39C-associated genes across cancer lineages are RNA5SP251, MIR6728, and UIMC1. Each is linked with TTC39C in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC39C-to-partner and partner-to-TTC39C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP251 grouped by TTC39C-low versus TTC39C-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39C→partner) and Y-score (partner→TTC39C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNA5SP251 →	+0.310	+5.578	<.001	.004	3	2
UCEC	MIR6728 →	+0.433	+1.891	.003	<.001	3	2
SKCM	UIMC1 →	+0.580	+3.208	.005	.009	3	2
UCEC	RNF214 →	+0.377	+2.609	.002	<.001	3	2
CESC	AK3P4 →	+0.066	+4.539	<.001	.008	3	2
UCEC	RNA5SP419 →	+0.461	+1.755	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,215 associations by consensus.

RNA5SP251 by TTC39C expression — HNSC

Explore this box plot interactively →