TTC39C

Across TCGA pan-cancer cohorts, TTC39C RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TTC39C’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TTC39C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TTC39C is over-expressed in tumor, although a few such as CHOL and KICH show the opposite, repressed pattern.

LUAD, KIRC, and COAD are the cancer types where TTC39C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TTC39C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+1.633	<.001	11	view →
KIRC	Male	All	+0.579	<.001	8	view →
COAD	Male	All	+0.427	<.001	7	view →
LUSC	Female	All	+1.186	<.001	6	view →
KIRP	All	All	+0.638	<.001	6	view →
CHOL	Male	All	−1.259	<.001	5	view →
KICH	All	All	−0.685	<.001	5	view →
STAD	All	All	+0.525	.005	4	view →
BRCA	All	II,III,IV	+0.320	.001	4	view →
ESCA	All	All	+0.677	.031	2	view →
READ	All	All	+0.427	.034	2	view →
THCA	All	IV	+0.899	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TTC39C–LUAD

Open the LUAD breakdown →