TTC39C

Across TCGA cell cohorts, TTC39C mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TTC39C-associated genes across cancer lineages are OR5P3, AADACL4, and C10orf71. Each is linked with TTC39C in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC39C-to-partner and partner-to-TTC39C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5P3 grouped by TTC39C-low versus TTC39C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39C→partner) and Y-score (partner→TTC39C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR5P3 →	+0.108	+5.201	<.001	.006	3	1
BLOOD_Leukemia	AADACL4 →	+0.026	+4.922	<.001	.009	3	1
CNS	C10orf71 →	+0.016	+4.981	<.001	.008	3	1
CNS	PRAMEF15 →	+0.352	+4.981	<.001	.008	3	1
CNS	LEUTX →	+0.181	+5.321	<.001	.005	3	1
CNS	MBD3L2 →	+1.117	+4.981	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

OR5P3 by TTC39C expression — BLOOD_Leukemia

Explore this box plot interactively →