TTC36

Across TCGA cell cohorts, TTC36 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,517 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC36-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Positive regulation of proteasomal ubiquitin-dependent protein catabolic process, and Negative regulation of autophagy. Each is linked with TTC36 in more than 12 cancer types. Because this analysis shows association rather than direction, both TTC36-to-partner and partner-to-TTC36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by TTC36-low versus TTC36-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC36→partner) and Y-score (partner→TTC36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to nucleus →	+0.088	+0.281	<.001	<.001	3	13
URINARY_TRACT	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.075	+0.378	<.001	<.001	3	12
STOMACH	Negative regulation of autophagy →	+0.084	+0.383	<.001	.002	3	11
STOMACH	Negative regulation of myoblast fusion →	+0.118	+0.398	<.001	<.001	3	10
URINARY_TRACT	Regulation of protein localization to endoplasmic reticulum →	+0.122	+0.435	<.001	.001	2	11
LUNG_SCLC	Regulation of nucleocytoplasmic transport →	+0.078	+0.696	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,517 associations by consensus.

Regulation of protein localization to nucleus by TTC36 expression — UPPER_AERODIGESTIVE_TRACT

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