TTC36

Across TCGA pan-cancer cohorts, TTC36 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TTC36 data layer compared with 1 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TTC36 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TTC36 expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRP show a favorable association.

BRCA, KIRP, and UCS are the cancer types where TTC36 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.950	0.897	<.001	108	view →
KIRP	OS	Quartile	II,III,IV	0.719	0.345	.001	62	view →
UCS	DFS	Quartile	II,III,IV	0.589	0.175	.006	60	view →
LIHC	OS	Tertile	All	0.805	0.621	<.001	48	view →
READ	OS	Median	All	1.000	0.804	.002	37	view →
CESC	DFS	Median	All	0.770	0.870	.004	30	view →
THCA	DFS	Quartile	III,IV	0.671	0.935	.004	26	view →
SKCM	OS	Median	IV	0.775	0.230	.008	20	view →
ACC	OS	Quartile	II,III,IV	0.356	0.680	.012	17	view →
MESO	OS	Tertile	IV	0.778	0.292	.012	12	view →
PRAD	DFS	Tertile	All	0.858	0.935	.017	12	view →
LGG	OS	Median	All	0.938	0.835	.001	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TTC36–BRCA (OS)

Open the BRCA breakdown →