TTC36

Across TCGA pan-cancer cohorts, TTC36 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TTC36’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where TTC36 RNA is repressed in tumor relative to normal tissue. In most cancer types TTC36 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and LIHC are the cancer types where TTC36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TTC36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	III,IV	−2.912	<.001	11	view →
KIRC	Male	All	−1.989	<.001	11	view →
LIHC	Female	II,III,IV	−5.026	<.001	8	view →
KICH	Male	II,III,IV	−2.062	<.001	8	view →
CHOL	Female	All	−6.846	<.001	5	view →
THCA	Male	All	−0.553	<.001	5	view →
LUSC	Male	II,III,IV	+0.228	.009	4	view →
STAD	All	All	−0.736	.016	3	view →
ESCA	All	II,III,IV	−0.400	.042	2	view →
PRAD	All	All	+0.216	.042	2	view →
LUAD	Female	II,III,IV	−0.164	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TTC36–KIRP

Open the KIRP breakdown →