TTC29

Across TCGA patient cohorts, TTC29 mutation is significantly associated with the RNA expression of many other genes, with 2,899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC29-associated genes across cancer lineages are IGHVIII-22-2, HDHD5-AS1, and KIF18B. Each is linked with TTC29 in more than 2 cancer types. Because this analysis shows association rather than direction, both TTC29-to-partner and partner-to-TTC29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHVIII-22-2 grouped by TTC29-low versus TTC29-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC29→partner) and Y-score (partner→TTC29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IGHVIII-22-2 →	+0.699	+3.957	.004	.003	3	3
UCEC	HDHD5-AS1 →	+0.464	+3.616	.003	.001	3	2
UCEC	KIF18B →	+0.846	+2.917	<.001	<.001	3	2
UCEC	BLM →	+0.567	+3.177	<.001	<.001	3	2
UCEC	RNU4-58P →	+0.179	+2.396	<.001	.001	3	2
UCEC	MIR615 →	+0.168	+1.980	.006	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,899 associations by consensus.

IGHVIII-22-2 by TTC29 expression — COAD

Explore this box plot interactively →