TTC29

Across TCGA pan-cancer cohorts, TTC29 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of TTC29’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TTC29 RNA is repressed in tumor relative to normal tissue. In most cancer types TTC29 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where TTC29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TTC29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.325	<.001	9	view →
KIRC	All	III,IV	−0.322	<.001	9	view →
LUSC	Female	II,III,IV	−1.888	<.001	8	view →
LUAD	All	II,III,IV	−1.316	<.001	8	view →
KICH	Male	All	−0.419	<.001	8	view →
COAD	All	All	+0.406	.041	3	view →
UCEC	All	All	−1.065	.031	2	view →
PRAD	All	All	+0.170	.043	2	view →
LIHC	Female	All	+0.018	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

TTC29–THCA

Open the THCA breakdown →