TTC26

Across TCGA cell cohorts, TTC26 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TTC26-associated genes across cancer lineages are IFNA17, FAM240B, and OR2T7. Each is linked with TTC26 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC26-to-partner and partner-to-TTC26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA17 grouped by TTC26-low versus TTC26-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC26→partner) and Y-score (partner→TTC26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNA17 →	+0.032	+5.539	<.001	.003	3	1
BLOOD_Leukemia	FAM240B →	+0.019	+5.969	<.001	.001	3	1
LUNG_SCLC	OR2T7 →	+0.006	+5.643	<.001	.002	3	1
LARGE_INTESTINE	NXF5 →	+0.020	+2.560	<.001	.008	3	1
CNS	HELT →	+0.037	+5.321	<.001	.005	3	1
SKIN	SCGB1D1 →	+0.056	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

IFNA17 by TTC26 expression — BLOOD_Leukemia

Explore this box plot interactively →