TTC21B

Across TCGA patient cohorts, TTC21B RNA expression is significantly associated with the protein abundance of many other proteins, with 18,927 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTC21B-associated proteins across cancer lineages are ZNF638, NCOR1, and IFT122. Each is linked with TTC21B in more than 4 cancer types. Because this analysis shows association rather than direction, both TTC21B-to-partner and partner-to-TTC21B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC21B versus ZNF638 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC21B→partner) and Y-score (partner→TTC21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF638 →	+0.232	+0.505	<.001	<.001	3	5
GBM	NCOR1 →	+0.355	+0.470	<.001	<.001	3	5
UCEC	IFT122 →	+0.306	+0.348	<.001	<.001	3	5
LSCC	PTBP2 →	+0.952	+0.426	<.001	.002	3	5
HNSC	BCL11A_S432 →	+0.946	+0.850	<.001	<.001	3	5
BRCA	CREBBP →	+0.208	+0.419	.008	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,927 associations by consensus.

TTC21B vs ZNF638 — LSCC

Explore this scatter interactively →