TTC21B

Across TCGA patient cohorts, TTC21B protein abundance is significantly associated with the RNA expression of many other genes, with 12,568 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTC21B-associated genes across cancer lineages are TSNAXIP1, PACRG, and FBXO36. Each is linked with TTC21B in more than 6 cancer types. Because this analysis shows association rather than direction, both TTC21B-to-partner and partner-to-TTC21B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC21B versus TSNAXIP1 in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC21B→partner) and Y-score (partner→TTC21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSNAXIP1 →	+0.923	+0.273	<.001	<.001	3	7
OV	PACRG →	+1.138	+0.263	<.001	.007	3	7
BRCA	FBXO36 →	+0.803	+0.265	<.001	<.001	3	7
UCEC	RSPH1 →	+1.424	+0.316	<.001	<.001	3	7
BRCA	DRC3 →	+0.972	+0.322	<.001	<.001	3	7
UCEC	CFAP91 →	+1.096	+0.370	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,568 associations by consensus.

TTC21B vs TSNAXIP1 — UCEC

Explore this scatter interactively →