TTBK2

Across TCGA patient cohorts, TTBK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,487 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTBK2-associated proteins across cancer lineages are HDGFL3, SEPTIN11, and RPL5. Each is linked with TTBK2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TTBK2-to-partner and partner-to-TTBK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTBK2 versus HDGFL3 in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTBK2→partner) and Y-score (partner→TTBK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HDGFL3 →	+0.583	+0.464	<.001	<.001	3	8
BRCA	SEPTIN11 →	+0.395	+0.525	<.001	<.001	3	7
CCRCC	RPL5 →	-0.217	-0.246	.001	<.001	3	7
GBM	MAP1A →	+0.591	+0.569	<.001	<.001	3	7
OV	PPIF →	-0.624	-0.863	<.001	<.001	3	6
UCEC	RAI14 →	+0.416	+0.317	.001	.007	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,487 associations by consensus.

TTBK2 vs HDGFL3 — GBM

Explore this scatter interactively →