TTBK1

Across TCGA patient cohorts, TTBK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,012 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTBK1-associated proteins across cancer lineages are CYFIP2, ENOSF1, and EPN3. Each is linked with TTBK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TTBK1-to-partner and partner-to-TTBK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTBK1 versus CYFIP2 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTBK1→partner) and Y-score (partner→TTBK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYFIP2 →	+0.474	+0.691	<.001	<.001	3	3
GBM	ENOSF1 →	-0.568	-0.476	<.001	<.001	3	3
OV	EPN3 →	-0.640	-0.312	.001	.001	3	3
LSCC	PKN1_S562 →	+0.632	+0.313	.007	.003	2	4
HNSC	SAMHD1_T592 →	+0.705	+0.197	<.001	<.001	3	3
OV	SYPL1 →	-0.663	-0.381	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,012 associations by consensus.

TTBK1 vs CYFIP2 — GBM

Explore this scatter interactively →